Human IL-12 R beta 1/CD212 Protein (ILR-HM212)
SKU: BTL-KB-P-02156 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ILR-HM212 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IL-12 R beta 1/CD212 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Cys24-Glu540. |
| Target | IL-12 R beta 1/CD212 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected by activation. Furthermore following its expression the IL12RB1 pre-mRNA is processed into either IL12RB1 Isoform 1 (IL12Rβ1, a positive regulator of IL12 responsiveness) or IL12RB1 Isoform 2 (a protein of heretofore unknown function). |
| Molecular Mass | The protein has a predicted MW of 83.85 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Cys24-Glu540 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P42701-1 |
| Amino Acid Sequence | Recombinant Human IL-12 R beta 1/CD212 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Cys24-Glu540. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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