Non-biotinylated Human IL-22R alpha 1&IL-10R beta Protein (ILR-HM2AB)
SKU: BTL-KB-P-02164 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ILR-HM2AB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IL-22R alpha 1&IL-10R beta Protein is expressed from HEK293 with hFc (IgG1) tag and Avi Tag at the C-Terminus of IL-22R alpha 1 and IL-10R beta.It contains His16-Thr228 (IL-22R alpha 1) and Met20-Ser220 (IL-10R beta). |
| Target | IL-22R alpha 1&IL-10R beta |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | IL-22Rα1 & IL-10Rβ are receptors for IL-22 and IL-10, mediate the activation of JAK-STAT, MAPK and other signaling pathways, and participate in the process of many inflammatory diseases. IL-22 Rα1 contains cytoplasmic motifs for interactions with signal transduction molecules, but formation of ternary complexes with IL10 Rβ or IL20 Rβ and the respective ligands is required for signal transduction. |
| Molecular Mass | The protein has a predicted MW of 52.07 kDa (IL-22R alpha 1) and 48.85 kDa (IL-10R beta). Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | His16-Thr228(IL-22R alpha 1) & Met20-Ser220(IL-10R beta) |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q8N6P7(IL-22R alpha 1)&Q08334(IL-10R beta) |
| Amino Acid Sequence | Recombinant Human IL-22R alpha 1&IL-10R beta Protein is expressed from HEK293 with hFc (IgG1) tag and Avi Tag at the C-Terminus of IL-22R alpha 1 and IL-10R beta.It contains His16-Thr228 (IL-22R alpha 1) and Met20-Ser220 (IL-10R beta). |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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