Human IL-1R3/IL-1 RAcP Protein (ILR-HM2R3)
SKU: BTL-KB-P-02168 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ILR-HM2R3 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser21-Glu359. |
| Target | IL-1R3/IL-1 RAcP |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. |
| Molecular Mass | The protein has a predicted MW of 65.8 kDa. Due to glycosylation, the protein migrates to 75-85 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser21-Glu359 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q9NPH3-1 |
| Amino Acid Sequence | Recombinant Human IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser21-Glu359. |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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