Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-CM1AB)
SKU: BTL-KB-P-02203 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-CM1AB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus of ITGA2.It contains Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail. |
| Target | Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis. |
| Molecular Mass | The protein has a predicted MW of 126.69 kDa (ITGA2) and 83.16 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-170 kDa (ITGA2) and 100-130 kDa (ITGB1) based on Bis-Tris PAGE result. |
| Sl Sequence | Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | G8F2Z5(ITGA2)&A0A7N9D0D7(ITGB1) |
| Amino Acid Sequence | Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus of ITGA2.It contains Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
Share Item: