Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-CM1V3)
SKU: BTL-KB-P-02204 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-CM1V3 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAV.It contains Phe31-Pro993(ITGAV) acidic tail and Gly27-Asp718(ITGB3) basic tail. |
| Target | Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Molecular Mass | The protein has a predicted MW of 112.31 kDa (ITGAV) & 81.27 kDa (ITGB3). Due to glycosylation, the protein migrates 95-140 to kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Phe31-Pro993(ITGAV) acidic tail & Gly27-Asp718(ITGB3) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A2K5WCD3(ITGAV)&A0A2K5WYN9(ITGB3) |
| Amino Acid Sequence | Recombinant Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAV.It contains Phe31-Pro993(ITGAV) acidic tail and Gly27-Asp718(ITGB3) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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