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Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein (ITG-HM110)

SKU: BTL-KB-P-02205 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number ITG-HM110
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA10.It contains Phe23-Ser1122(ITGA10) acidic tail and Gln21-Asp728(ITGB1) basic tail.
Target Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer
Host Human
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background Alpha 10 beta 1 is currently known as four collagen-binding I domain-containing integrins, the others are namely alpha 1 beta 1, alpha 2 beta 1 and alpha 11 beta 1. α10β1 is likely to be expressed only by a subset of fibroblasts.
Molecular Mass The protein has a predicted MW of 125.60 kDa (ITGA10) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-160 kDa (ITGA10) and 110-120 kDa (ITGB1) based on Bis-Tris PAGE result.
Sl Sequence Phe23-Ser1122(ITGA10) acidic tail & Gln21-Asp728(ITGB1) basic tail
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id O75578-1(ITGA10)&P05556-1(ITGB1)
Amino Acid Sequence Recombinant Human Integrin alpha 10 beta 1 (ITGA10&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA10.It contains Phe23-Ser1122(ITGA10) acidic tail and Gln21-Asp728(ITGB1) basic tail.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Note The product is for research use only
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