Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein (ITG-HM18B)
SKU: BTL-KB-P-02207 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-HM18B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA8.It contains Phe39-Leu1012(ITGA8) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Target | Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Human Integrin alpha 8 beta 1 is a heterodimeric glycoprotein composed of integrin alpha 8 and integrin beta 1 that mainly expressed in smooth muscle cells. It functions as a receptor for Tenascin, Fibronectin, and Vitronectin and can promote attachment, cell spreading, and neurite outgrowth. |
| Molecular Mass | The protein has a predicted MW of 113.90 kDa (ITGA8) & 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 120-140 kDa (ITGA8) and 100-120 kDa (ITGB1) based on Bis-Tris PAGE result. |
| Sl Sequence | Phe39-Leu1012(ITGA8) acidic tail & Gln21-Asp728(ITGB1) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P53708(ITGA8)&P05556-1(ITGB1) |
| Amino Acid Sequence | Recombinant Human Integrin alpha 8 beta 1 (ITGA8&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA8.It contains Phe39-Leu1012(ITGA8) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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