Non-biotinylated Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein (ITG-HM441)
SKU: BTL-KB-P-02217 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-HM441 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Tyr34-Thr977(ITGA4) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Target | Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. |
| Molecular Mass | The protein has a predicted MW of 112.5 kDa (ITGA4) and 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 70-90 kDa and 120-160 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Tyr34-Thr977(ITGA4) acidic tail & Gln21-Asp728(ITGB1) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P13612-1(ITGA4)&P05556-1(ITGB1) |
| Amino Acid Sequence | Recombinant Human Integrin alpha 4 beta 1 (ITGA4&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Tyr34-Thr977(ITGA4) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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