Non-biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein (ITG-HM4V8)
SKU: BTL-KB-P-02235 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-HM4V8 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of ITGAV.It contains Phe31-Val992(ITGAV) acidic tail and Glu43-Arg684(ITGB8) basic tail. |
| Target | Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
| Scientific Background | Integrin αVβ8 is a heterodimeric cell surface receptor involved in various cellular processes, including cell adhesion, migration, and signaling. It is recognized for its unique role in activating TGF-β and has been implicated in immune responses and tissue homeostasis. Due to its distinctive structure and function, integrin αVβ8 is considered atypical among integrin family members. |
| Molecular Mass | The protein has a predicted MW of 114 kDa (ITGAV) and 76 kDa (ITGB8). Due to glycosylation, the protein migrates to 90-150 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P06756-1(ITGAV)&P26012-1(ITGB8) |
| Amino Acid Sequence | Recombinant Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of ITGAV.It contains Phe31-Val992(ITGAV) acidic tail and Glu43-Arg684(ITGB8) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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