Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)
SKU: BTL-KB-P-02241 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | ITG-MM1AB |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA2.It contains Tyr27-Thr1129(ITGA2) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Target | Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.HOS cells normally lacking alpha 2 beta 1 integrin were forced to express it, and this prevented the down-regulation in the levels of alpha 1 (I) collagen mRNA when cells were grown inside collagen gels. The data indicate that the level of MMP-1 expression is regulated by the collagen receptor alpha 2 beta 1 integrin. |
| Molecular Mass | The protein has a predicted MW of 126.60 kDa(ITGA2)&82.80 kDa(ITGB1). Due to glycosylation, the protein migrates to 128-138 kDa(ITGA2)&105-115 kDa(ITGB1) based on Bis-Tris PAGE result. |
| Sl Sequence | Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q62469(ITGA2)&P09055-1(ITGB1) |
| Amino Acid Sequence | Recombinant Mouse Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA2.It contains Tyr27-Thr1129(ITGA2) acidic tail and Gln21-Asp728(ITGB1) basic tail. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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