Non-biotinylated Human KIR2DL3 Protein (KIR-HM4L3)
SKU: BTL-KB-P-02267 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | KIR-HM4L3 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245. |
| Target | KIR2DL3 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
| Molecular Mass | The protein has a predicted MW of 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | His22-His245 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P43628 |
| Amino Acid Sequence | Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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