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Non-biotinylated Human KIR2DL3 Protein, Ultra Low Endotoxin (KIR-HM4L3-UL)

SKU: BTL-KB-P-02268 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number KIR-HM4L3-UL
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
Target KIR2DL3
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Molecular Mass The protein has a predicted MW of 27.3 kDa. Due to glycosylation, the protein migrates to 45-52 kDa based on Bis-Tris PAGE result.
Sl Sequence His22-His245
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 0.01 EU per μg by the LAL method.
Expression System HEK293
Gene Id P43628
Amino Acid Sequence Recombinant Human KIR2DL3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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