Human Kallikrein 1/KLK1 Protein (active form) (KLK-HM101)
SKU: BTL-KB-P-02282 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | KLK-HM101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Kallikrein 1/KLK1 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile25-Ser262. |
| Target | Kallikrein 1/KLK1 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | KLK1 (tissue kallikrein 1) is a member of the tissue kallikrein family of serine proteases, which, in humans, comprises 15 proteases and constitutes the largest contiguous cluster of any family of proteases on the human genome. KLK1 cleaves both low-molecular-mass kininogen and HMMK (high-molecular-mass kininogen) at two sites to release the decapeptide kinin Lys-bradykinin (Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg). |
| Molecular Mass | The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ile25-Ser262 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P06870-1 |
| Amino Acid Sequence | Recombinant Human Kallikrein 1/KLK1 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile25-Ser262. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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