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Human Kallikrein 4/KLK4 Protein (active form), Ultra Low Endotoxin (KLK-HM104-UL)

SKU: BTL-KB-P-02287 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number KLK-HM104-UL
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human Kallikrein 4/KLK4 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile31-Ser254.
Target Kallikrein 4/KLK4
Host Human
Purity > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Scientific Background Human tissue kallikrein 4 (hK4) is a member of a highly conserved gene family which contains 15 human enzymes composed of closely related serine proteases. The hK4 enzyme is a subgroup of the serine proteases that catalyzes the cutting of the peptide backbone in proteins via hydrolysis. kallikreins been known to catalyze the break down of bradykininogen to bradykinin and plasminogen to plasmin, in addition to being active in initiating intracellular signaling through protease-activated receptors.
Molecular Mass The protein has a predicted MW of 25.61 kDa. Due to glycosylation, the protein migrates to 27-37 kDa based on Bis-Tris PAGE result.
Sl Sequence Ile31-Ser254
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 0.01 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q9Y5K2-1
Amino Acid Sequence Recombinant Human Kallikrein 4/KLK4 Protein (active form) is expressed from HEK293 with His tag at the C-terminus.It contains Ile31-Ser254.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Note The product is for research use only
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