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Dorsomorphin

SKU: BTL-IB-P-00107 | Brand: Isca Biochemical

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Product Description

Cat Number	KS-300
Category	Peptide
Pack Size	5 mg
Description	AMPK inhibitor
Purity	98% by TLC, NMR conforms
Biomarker Target	Kinases,Receptor serine/threonine kinase receptors
Sequence Three Letter Code	6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
Molecular Formula	C24H25N5O
Solubility	Soluble in DMSO to 3 mg/ml
Appearance	Pale yellow solid
Storage	Store dry, frozen and in the dark
References	Yu et al (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 4(1) 33 PMID: 18026094Hao et al (2008) Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells. PLoS One 3(8) e2904 PMID: 18682835Vucicevic et al (2011) Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy (1) 40 PMID: 20980833Aikawa et al (2020) Cell death induced by dorsomorphin in adult T-cell leukemia/lymphoma is AMPK-independent. FEBS J. 287(18) 4005 PMID: 32027454Xinqiang et al (2022) Systemic administration of dorsomorphin relieves inflammatory nociception in the mouse formalin test. Int Immunopharmacol. 113(Pt A) 109337 PMID: 36274489 Related areas All small molecules >All kinase modulators >All cancer research categories >All stem cell research categories >All regulated cell death research categories >All pain research categories >
Note	The product is for research use only

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