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Go 6983

SKU: BTL-IB-P-00151 | Brand: Isca Biochemical
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Product Description

Cat Number KS-330
Category Peptide
Pack Size 1 mg
Description PKC inhibitor
Purity 98% by HPLC, NMR conforms
Biomarker Target Kinases,Transferases
Sequence Three Letter Code 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Molecular Formula C26H26N4O3
Solubility Soluble in DMSO to 20 mg/ml
Appearance Orange solud
Storage Store dry, frozen and in the dark
References Gschwendt et al (1996) Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 392(2) 77 PMID: 8772178Peterman et al (2004) Gö 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion. J Cardiovasc Pharmacol. 43(5) 645 PMID: 15071351Young et al (2005) Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. Cardiovasc Drug Rev. 23(3):255 PMID: 16252018Gafni et al (2013) Derivation of novel human ground state naive pluripotent stem cells. Nature 504(7479) 282 PMID: 24172903Ji et al (2024) Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation. J Biol Chem. Feb 1 105714 PMID: 38309502
Related areas
All small molecules >All kinase inhibitors >All transferase inhibitors >All stem cell research categories >All epigenetic research categories >
Note The product is for research use only
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