Product Description
| Cat Number | LGR-HM205 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human LGR-5 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gly22-Pro543. |
| Target | LGR-5 |
| Host | Human |
| Purity | > 90% as determined by Bis-Tris PAGE |
| Scientific Background | G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma. |
| Molecular Mass | The protein has a predicted MW of 85 kDa. Due to glycosylation, the protein migrates to 110-120 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gly22-Pro543 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | O75473-1 |
| Amino Acid Sequence | Recombinant Human LGR-5 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gly22-Pro543. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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