Product Description
| Cat Number | LRP-HM316 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human LRP-6 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ala20-Pro630. |
| Target | LRP-6 |
| Host | Human |
| Purity | > 90% as determined by Bis-Tris PAGE |
| Scientific Background | Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/β-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimer's disease and osteoporosis. LRP-6 interacts closely with PDGF receptor β and TGF-β receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/β-catenin. |
| Molecular Mass | The protein has a predicted MW of 95.32 kDa. Due to glycosylation, the protein migrates to 97-110 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala20-Pro630 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | O75581-1 |
| Amino Acid Sequence | Recombinant Human LRP-6 Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ala20-Pro630. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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