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Cynomolgus LY6G6D Protein (LYD-CM16D)

SKU: BTL-KB-P-02481 | Host: Cynomolgus | Brand: Kactus Bio
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Product Description

Cat Number LYD-CM16D
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Cynomolgus LY6G6D Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn20-Ser104.
Target LY6G6D
Host Cynomolgus
Purity > 95% as determined by Bis-Tris PAGE
Scientific Background LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
Molecular Mass The protein has a predicted MW of 10.22 kDa. Due to glycosylation, the protein migrates to 14-24 kDa based on Bis-Tris PAGE result.
Sl Sequence Asn20-Ser104
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id XP_014991478.1
Amino Acid Sequence Recombinant Cynomolgus LY6G6D Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn20-Ser104.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Note The product is for research use only
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