Human LY6G6D Protein (LYD-HM66D)
SKU: BTL-KB-P-02488 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | LYD-HM66D |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human LY6G6D Protein is expressed from HEK293 with His tag and Spy tag at the C-terminus.It contains Asn20-Ser104. |
| Target | LY6G6D |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. |
| Molecular Mass | The protein has a predicted MW of 12.6 kDa. Due to glycosylation, the protein migrates to 15-25 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Asn20-Ser104 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 0.1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | O95868 |
| Amino Acid Sequence | Recombinant Human LY6G6D Protein is expressed from HEK293 with His tag and Spy tag at the C-terminus.It contains Asn20-Ser104. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | The product is for research use only |
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