Product Description
| Cat Number | MAP-HM2P5 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ile22-Leu173. |
| Target | MFAP5 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. |
| Molecular Mass | The protein has a predicted MW of 44.1 kDa. Due to furin cleavage and glycosylation, the protein migrates to 32-38 kDa and 55-65 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ile22-Leu173 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q13361-1 |
| Amino Acid Sequence | Recombinant Human MFAP5 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ile22-Leu173. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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