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Biotinylated Cynomolgus MADCAM1 Protein (MCM-CM401B)

SKU: BTL-KB-P-02508 | Host: Cynomolgus | Brand: Kactus Bio
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Product Description

Cat Number MCM-CM401B
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Biotinylated Cynomolgus MADCAM1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln22-Gln295.
Target MADCAM1
Host Cynomolgus
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Mucosal addressin cell adhesion molecule–1 (MAdCAM-1) is an endothelial cell marker that is recognized by its ligands on lymphocytes: L-selectin and α4β7 integrin. MAdCAM-1 is highly expressed on intestinal endothelium and has, recently, been shown to play an important role in the development of acute GVHD in animal model.
Molecular Mass The protein has a predicted MW of 31.95 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Sl Sequence Gln22-Gln295
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id XP_045235080.2
Amino Acid Sequence Recombinant Biotinylated Cynomolgus MADCAM1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln22-Gln295.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note The product is for research use only
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