Human MERTK/Mer Protein (MEK-HM301)
SKU: BTL-KB-P-02521 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MEK-HM301 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MERTK/Mer Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ala21-Ile505. |
| Target | MERTK/Mer |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. |
| Molecular Mass | The protein has a predicted MW of 78.9 kDa. Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ala21-Ile505 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q12866-1 |
| Amino Acid Sequence | Recombinant Human MERTK/Mer Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ala21-Ile505. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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