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Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein (MHC-HE002B)

SKU: BTL-KB-P-02546 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number MHC-HE002B
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide.
Target HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK)
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
Molecular Mass The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Sl Sequence Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide
Appearance Liquid
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System E.coli
Gene Id AAV53343.1 (HLA-A*11:01)&P61769 (B2M)&VVGAGGVGK
Amino Acid Sequence Recombinant Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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