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Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein (MHC-HE009B)

SKU: BTL-KB-P-02562 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number MHC-HE009B
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide.
Target HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV)
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identified Rab protein that may downregulate TLR4 and TLR9-mediated inflammatory responses. Rab7b, believed to have similar function as Rab7, controls however vesicular trafficking from endosomes to the TGN. It is localized to late endosomes/lysosomes as well as the TGN. Rab7b interferes with enzymes delivery to lysosomes and with the retrograde Shiga toxin transport to the Golgi.
Molecular Mass The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Sl Sequence Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide
Appearance Liquid
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System E.coli
Gene Id A0A140T913(HLA-A*02:01)&P61769(B2M)&KLIIVGAIGV
Amino Acid Sequence Recombinant Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Note The product is for research use only
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