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Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein (MHC-HM104)

SKU: BTL-KB-P-02635 | Host: Human&Mouse | Brand: Kactus Bio
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Product Description

Cat Number MHC-HM104
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr206 (Human HLA-A*02:01 α1&α2) and Asp207-Glu299 (Mouse H-2Ld α3), Ile21-Met119 (mB2M) and KMVELVHFL peptide.
Target HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL)
Host Human&Mouse
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Melanoma antigen gene (MAGE)-A2 (MAGEA2) is a member of the MAGE-A family proteins widely studied for cancer vaccine development and identification of tumor markers. MAGEA2 plays an oncogenic role in glioma progression, and they provide insight into MAGEA2 application as a novel predictor of clinical outcomes and a potential glioma biomarker.
Molecular Mass The protein has a predicted MW of 48.00 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Sl Sequence Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and KMVELVHFL peptide
Appearance Liquid
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse H-2Ld α3)&&P01887(Mouse B2M)&KMVELVHFL
Amino Acid Sequence Recombinant Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A2 (KMVELVHFL) Monomer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr206 (Human HLA-A*02:01 α1&α2) and Asp207-Glu299 (Mouse H-2Ld α3), Ile21-Met119 (mB2M) and KMVELVHFL peptide.
Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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