Human HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein (MHC-HM427)
SKU: BTL-KB-P-02725 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MHC-HM427 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MAGE-A3(HLA-A*01:01) Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M) and EVDPIGHLY peptide. |
| Target | HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa. |
| Molecular Mass | The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M) and EVDPIGHLY peptide |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q5SUL5(HLA-A*01:01)&P61769(B2M)&EVDPIGHLY |
| Amino Acid Sequence | Recombinant Human MAGE-A3(HLA-A*01:01) Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M) and EVDPIGHLY peptide. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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