APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM469TA)
SKU: BTL-KB-P-02829 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MHC-HM469TA |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide. |
| Target | HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) |
| Host | Human |
| Scientific Background | Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
| Sl Sequence | Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide |
| Appearance | Liquid |
| Expression System | HEK293 |
| Gene Id | P01889(HLA-B*07:02)&P61769(B2M)&GADGVGKSAL |
| Amino Acid Sequence | Recombinant APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide. |
| Storage | Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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| Note | The product is for research use only |
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