Biotinylated Human HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein (MHC-HM492B)
SKU: BTL-KB-P-02853 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MHC-HM492B |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Biotinylated Human HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide. |
| Target | HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL) |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. |
| Molecular Mass | The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | AAA59688.1(HLA-C*08:01)&P61769(B2M)&GADGVGKSAL |
| Amino Acid Sequence | Recombinant Biotinylated Human HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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