Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Monomer Protein (MHC-HM493)
SKU: BTL-KB-P-02856 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MHC-HM493 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and ILNNFPHSI peptide. |
| Target | HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | ILNNFPHSI is a peptide epitope derived from KKLC1 (also known as Kita-kyushu lung cancer antigen 1, CT83 or CXorf61) that is naturally processed and presented on the cell surface in complex with MHC class I molecules. This peptide, together with binding moieties that specifically recognize the peptide–MHC complex, provides a valuable basis for the development of therapeutic agents capable of selectively targeting KKLC1-expressing cancer cells, and holds particular promise for the treatment of malignancies such as non-small cell lung cancer (adenocarcinoma and squamous subtypes) and esophageal cancer. |
| Molecular Mass | The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A140T913(HLA-A*02:01)&P61769(B2M)&ILNNFPHSI |
| Amino Acid Sequence | Recombinant Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and ILNNFPHSI peptide. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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