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Batimastat

SKU: BTL-IB-P-00061 | Brand: Isca Biochemical
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Product Description

Cat Number MM-010
Category Peptide
Pack Size 1 mg
Description Matrix metalloproteinase inhibitor 
Purity 98% by HPLC, NMR conforms
Biomarker Target Matrix metalloproteases
Sequence Three Letter Code (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
Molecular Formula C23H31N3O4S2
Solubility Soluble in DMSO to 45 mg/ml
Appearance White solid
Storage Store dry, frozen and in the dark
References Davies et al (1993) A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res. 53(9) 2087 PMID: 8347186Kohn and Liotta (1995) Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res. 55(9) 1856 PMID: 7728753Lein et al (2000) Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model. Prostate 43(2) 77 PMID: 10754522Park et al (2011) Matrix metalloproteinase inhibitors attenuate neuroinflammation following focal cerebral ischemia in mice. Korean J Physiol Pharmacol. 15(2) 115 PMID: 21660152Mustafa et al (2022) Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A Review. Front Mol Biosci. 9 896099 PMID: 36250005
Related areas
All small molecules >All matrix metalloproteinase modulators >All cancer research categories >
Note The product is for research use only
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