Human MSLN/Mesothelin Protein (MSL-HM280)
SKU: BTL-KB-P-02947 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MSL-HM280 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MSLN/Mesothelin Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu296-Gly580. |
| Target | MSLN/Mesothelin |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally. |
| Molecular Mass | The protein has a predicted MW of 59 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu296-Gly580 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q13421-2 |
| Amino Acid Sequence | Recombinant Human MSLN/Mesothelin Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu296-Gly580. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |

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