Human Mucin-1/MUC-1 Isoform Y Protein, Ultra Low Endotoxin (MUC-HM2Y1-UL)
SKU: BTL-KB-P-02975 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | MUC-HM2Y1-UL |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human Mucin-1/MUC-1 Isoform Y Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser24-Gly158. |
| Target | Mucin-1/MUC-1 |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. |
| Molecular Mass | The protein has a predicted MW of 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser24-Gly158 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 0.01 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | P15941-7 |
| Amino Acid Sequence | Recombinant Human Mucin-1/MUC-1 Isoform Y Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser24-Gly158. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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