Product Description
| Cat Number | MVK-HB101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396. |
| Target | MVK |
| Host | Human |
| Purity | > 90% as determined by Bis-Tris PAGE |
| Scientific Background | Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate. |
| Molecular Mass | The protein has a predicted MW of 72.23 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Met1-Leu396 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | Baculovirus-Insect Cells(Sf9) |
| Gene Id | Q03426 |
| Amino Acid Sequence | Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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