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Human NGAL/Lipocalin-2 Protein (NGL-HM201)

SKU: BTL-KB-P-03013 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number NGL-HM201
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human NGAL/Lipocalin-2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln21-Gly198.
Target NGAL/Lipocalin-2
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background Acute kidney injury (AKI) is one of the most common complications of various serious conditions, and early diagnosis is therefore critical for the treatment of AKI. Recent evidence demonstrates that neutrophil gelatinase- associated lipocalin (NGAL) is closely associated with AKI. Several experimental and clinical studies have shown that the expression of urine and serum NGAL increases significantly in AKI. NGAL shows potential to be a new effective early biochemical marker of AKI. Further studies are needed to confirm the significant advantages of NGAL in the diagnosis of early AKI and its value in clinical applications.
Molecular Mass The protein has a predicted MW of 47.2 kDa. Due to glycosylation, the protein migrates to 48-52 kDa based on Bis-Tris PAGE result.
Sl Sequence Gln21-Gly198
Solubility Dissolve the lyophilized protein in 50mM MES,150mM NaCl (pH 6.5). It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id P80188-1
Amino Acid Sequence Recombinant Human NGAL/Lipocalin-2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln21-Gly198.
Storage -20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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