Cynomolgus NKG2A&CD94 Protein (NKC-CM194)
SKU: BTL-KB-P-03016 |
Host: Cynomolgus |
Brand: Kactus Bio
Product Description
| Cat Number | NKC-CM194 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus NKG2A&CD94 Protein is expressed from HEK293 with His tag at the C-Terminus of NKG2A and Flag tag at the C-Terminus of CD94.It contains Pro94-Leu233(NKG2A) and Lys32-Ile179(CD94). |
| Target | NKG2A&CD94 |
| Host | Cynomolgus |
| Purity | > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
| Scientific Background | The ligand-receptor assignment between HLA-G and NKG2A/CD94 is dependent of the amino acid composition in the HLA-G heavy chain. Understanding the biophysical basis of receptor-mediated events that lead to NK cell inhibition would help to remove non-tumor reactive cells and support personalized mild autologous NK cell therapies. |
| Molecular Mass | The protein has a predicted MW of 17.01 kDa(NKG2A)&18.27 kDa(CD94). Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Pro94-Leu233(NKG2A) & Lys32-Ile179(CD94) |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q68VD2(NKG2A)&Q68VD4(CD94) |
| Amino Acid Sequence | Recombinant Cynomolgus NKG2A&CD94 Protein is expressed from HEK293 with His tag at the C-Terminus of NKG2A and Flag tag at the C-Terminus of CD94.It contains Pro94-Leu233(NKG2A) and Lys32-Ile179(CD94). |
| Storage | -20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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