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SKU: BTL-IB-P-00108 | Brand: Isca Biochemical

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Product Description

Cat Number	NR-230
Category	Peptide
Pack Size	5 mg
Description	ERβ receptor agonist
Purity	98% by TLC, NMR conforms
Biomarker Target	Nuclear receptor modulators
Sequence Three Letter Code	2,3-bis(4-Hydroxyphenyl)propionitrile
Molecular Formula	C15H13NO2
Solubility	Soluble in DMSO to 25 mg/ml or in ethanol to 20 mg/ml
Appearance	Off-white solid
Storage	Store dry, frozen and in the dark
References	Meyers et al (2001) Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem. 44(24) 4230 PMID: 11708925Waters et al (2009) Estrogen receptor alpha and beta specific agonists regulate expression of synaptic proteins in rat hippocampus. Brain Res. 1290 1 PMID: 19596275Lombardi et al (2016) Estrogen receptor beta (ERβ) mediates expression of β-catenin and proliferation in prostate cancer cell line PC-3. Mol Cell Endocrinol.430 12 PMID: 27107935Zhang et al (2016) Role of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis. World J Gastroenterol. 22(18) 4484 PMID: 27182159Souza (2023) Estrogen receptors regulate galectin€‘3 in androgen€‘independent DU€‘145 prostate cancer cells. Oncol Rep. 49(5) 93 PMID: 36960864 Related areas All small molecules >All nuclear receptor modulators >All endocrinology research categories >All cancer research categories >
Note	The product is for research use only

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