Product Description
| Cat Number | NRS-HE101 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human NRAS Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Cys186. |
| Target | NRAS |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM. |
| Molecular Mass | The protein has a predicted MW of 22.29 kDa same as Bis-Tris PAGE result. |
| Sl Sequence | Met1-Cys186 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | E.coli |
| Gene Id | P01111 |
| Amino Acid Sequence | Recombinant Human NRAS Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Cys186. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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