Cynomolgus/Rhesus macaque PD-L1/B7-H1 Protein (PDL-CM210)
SKU: BTL-KB-P-03192 |
Host: Cynomolgus/Rhesus macaque |
Brand: Kactus Bio
Product Description
| Cat Number | PDL-CM210 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Cynomolgus/Rhesus macaque PD-L1/B7-H1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Phe19-Arg238. |
| Target | PD-L1/B7-H1 |
| Host | Cynomolgus/Rhesus macaque |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. |
| Molecular Mass | The protein has a predicted MW of 52 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Phe19-Arg238 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | G7PSE7 |
| Amino Acid Sequence | Recombinant Cynomolgus/Rhesus macaque PD-L1/B7-H1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Phe19-Arg238. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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