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Human PD-L1/B7-H1 Protein (PDL-HM210)

SKU: BTL-KB-P-03198 | Host: Human | Brand: Kactus Bio
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Product Description

Cat Number PDL-HM210
Category Recombinant Protein
Pack Size 100UG
Description Recombinant Human PD-L1/B7-H1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Phe19-Arg238.
Target PD-L1/B7-H1
Host Human
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Scientific Background B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.
Molecular Mass The protein has a predicted MW of 52 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Bis-Tris PAGE result.
Sl Sequence Phe19-Arg238
Solubility Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Appearance Lyophilized
Endotoxin Levels Less than 1 EU per μg by the LAL method.
Expression System HEK293
Gene Id Q9NZQ7-1
Amino Acid Sequence Recombinant Human PD-L1/B7-H1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Phe19-Arg238.
Storage -20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Pdf View Document
Note The product is for research use only
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