Product Description
| Cat Number | PI-001 |
|---|---|
| Category | Peptide |
| Pack Size | 10 mg |
| Description | Ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor |
| Purity | ‰¥98% by HPLC |
| Biomarker Target | Deubiquitinating enzymes |
| Sequence Three Letter Code | 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime) |
| Molecular Formula | C17H11Cl3N2O3 |
| Sl Sequence | 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime) |
| Solubility | Soluble to 50 mM in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| References |
Liu et al (2003) Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem.Biol. 10 837 PMID: 14522054_x000D_
Tan et al (2008) Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. Mol.Cell.Biochem. 318 109 PMID: 18622688Cartier et al (2009) Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. J.Neurosci. 29 7857 PMID: 19535597 Related areasAll small molecules >All deubiquitinating enzyme modulators >All neuroscience research areas > |
| Note | The product is for research use only |
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