Canine PRLR Protein (PLR-DM201)
SKU: BTL-KB-P-03252 |
Host: Canine |
Brand: Kactus Bio
Product Description
| Cat Number | PLR-DM201 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Canine PRLR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln25-Thr235. |
| Target | PRLR |
| Host | Canine |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers. |
| Molecular Mass | The protein has a predicted MW of 53.89 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln25-Thr235 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | XM_038663941.1 |
| Amino Acid Sequence | Recombinant Canine PRLR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln25-Thr235. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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