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Foxy 5

SKU: BTL-IB-P-00129 | Brand: Isca Biochemical
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Product Description

Cat Number PP-110
Category Peptide
Pack Size 1 mg
Description Wnt5a mimetic peptide
Modification N-Formylated
Purity >95% by hplc
Biomarker Target Frizzled receptors
Sequence Three Letter Code N-Formyl-Met-Asp-Gly-Cys-Glu-Leu-OH
Molecular Formula C26H42N6O12S2
Sl Sequence N-Formyl-MDGCEL
Solubility Soluble to 1 mg/ml in PBS
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Säfholm et al (2006) A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 281 2740 PMID: 16330545Säfholm et al (2008) The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 14 6556 PMID: 18927296Canesin (2017) Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model. PLoS One 12(9) e0184418 PMID: 28886116
Related areas
All peptides >All frizzled receptor modulators >All cancer research categories >All stem cell research categories >
Note The product is for research use only
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