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KGYY15

SKU: BTL-IB-P-00174 | Brand: Isca Biochemical
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Product Description

Cat Number PP-410
Category Peptide
Pack Size 1 mg
Description Interacts with CD40
Modification None
Purity >95% by hplc
Biomarker Target Protein-protein interactions,Integrin receptors
Sequence Three Letter Code H-Val-Leu-Gln-Trp-Ala-Lys-Lys-Gly-Tyr-Tyr-Thr-Met-Lys-Ser-Asn-OH
Molecular Formula C84H129N21O22S
Sl Sequence VLQWAKKGYYTMKSN
Solubility Soluble in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark
References Vaitaitis et al (2014)  A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice. Diabetologia 57(11) 2366 PMID: 25104468Vaitaitis et al (2019) CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor. Reply to Pagni PP, Wolf A, Lo Conte M et al. Diabetologia 62(9) 1730 PMID: 31286154Vaitaitis and  Wagner (2023) Modulating CD40 and integrin signaling in the proinflammatory nexus using a 15-amino-acid peptide, KGYY15. J Biol Chem. 299(5) 104625 PMID: 36944397
Related areas
All peptides >All protein-protein interaction modulators >All integrin receptor modulators >All diabetes research categories >All immunology research categories >
Note The product is for research use only
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