Product Description
| Cat Number | PRA-MM201 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse PILRA Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu32-Val197. |
| Target | PILRA |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Paired immunoglobulin-like type 2 receptor alpha (PILRΑ), which is mainly expressed on immune cells, including macrophages, dendritic cells and granulocytes, is related to regulation of broad immune responses. Bearing two immunoreceptor tyrosine-based inhibition motifs (ITIMs) in its cytoplasmic domain, PILRΑ functions to transmit inhibitory signals by recruiting SHP-1 and SHP-2, upon recognition of ligands such as CD99, neuronal differentiation proliferation factor-1 and CD8A, etc. |
| Molecular Mass | The protein has a predicted MW of 45.4 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Glu32-Val197 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q2YFS3-1 |
| Amino Acid Sequence | Recombinant Mouse PILRA Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu32-Val197. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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