Product Description
| Cat Number | PS2-ME120 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gln24-Pro211. |
| Target | PS20 |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection. |
| Molecular Mass | The protein has a predicted MW of 21.9 kDa. The protein migrates to 27-30 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Gln24-Pro211 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | E.coli |
| Gene Id | Q9ESH5 |
| Amino Acid Sequence | Recombinant Mouse PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gln24-Pro211. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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