Human PVRIG Protein, Ultra Low Endotoxin (PVR-HM302-UL)
SKU: BTL-KB-P-03311 |
Host: Human |
Brand: Kactus Bio
Product Description
| Cat Number | PVR-HM302-UL |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Human PVRIG Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Thr41-Asp171. |
| Target | PVRIG |
| Host | Human |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. |
| Molecular Mass | The protein has a predicted MW of 40.03 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Thr41-Asp171 |
| Appearance | Liquid |
| Endotoxin Levels | Less than 0.01 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q6DKI7 |
| Amino Acid Sequence | Recombinant Human PVRIG Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Thr41-Asp171. |
| Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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