Non-biotinylated Mouse PVRIG Protein (PVR-MM501)
SKU: BTL-KB-P-03312 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | PVR-MM501 |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse PVRIG Protein is expressed from HEK293 with hFc (IgG1) tag and Avi tag at the C-Terminus.It contains Ser35-Asp165. |
| Target | PVRIG |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE |
| Scientific Background | Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. |
| Molecular Mass | The protein has a predicted MW of 42.70 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Ser35-Asp165 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | A0A1B0GS01 |
| Amino Acid Sequence | Recombinant Mouse PVRIG Protein is expressed from HEK293 with hFc (IgG1) tag and Avi tag at the C-Terminus.It contains Ser35-Asp165. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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