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DAPT

SKU: BTL-IB-P-00103 | Brand: Isca Biochemical

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Product Description

Cat Number	SC-010
Category	Peptide
Pack Size	5 mg
Description	Î³-Secretase inhibitor
Purity	98% by TLC, NMR conforms
Biomarker Target	Secretases
Sequence Three Letter Code	N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester
Molecular Formula	C23H26F2N2O4
Solubility	Soluble to 100 mM in DMSO
Appearance	White solid
Storage	Store dry, frozen and in the dark
References	Dovey (2001) Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J Neurochem. 76(1) 173 PMID: 11145990De Smedt et al (2005) Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment. Blood 106(10) 3498 PMID: 16030192Crawford and Roelink (2007) The notch response inhibitor DAPT enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independently of sonic hedgehog signaling. Dev Dyn. 236(3) 886 PMID: 17295317 Related areas All small molecules >All secretase modulators >All neuroscience research categories >All stem cell research categories >
Note	The product is for research use only

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