Mouse P-Selectin/CD62P Protein (SEL-MM10P)
SKU: BTL-KB-P-03389 |
Host: Mouse |
Brand: Kactus Bio
Product Description
| Cat Number | SEL-MM10P |
|---|---|
| Category | Recombinant Protein |
| Pack Size | 100UG |
| Description | Recombinant Mouse P-Selectin/CD62P Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Trp42-Ala709. |
| Target | P-Selectin/CD62P |
| Host | Mouse |
| Purity | > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
| Scientific Background | P-selectin is critical in the progression of atherosclerosis as evidenced by knockout animal models where P-selectin knockout mice crossed with apoE deficient mice exhibit significantly reduced atherosclerosis and leukocyte recruitment in the plaque. A soluble form of P-selectin also exists, which may have pro-atherogenic and pro-thrombotic effects. Thus targeting of P-selectin remains a strong clinical candidate for developing novel therapeutic strategies in inflammatory diseases. |
| Molecular Mass | The protein has a predicted MW of 81.1 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result. |
| Sl Sequence | Trp42-Ala709 |
| Solubility | Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
| Appearance | Lyophilized |
| Endotoxin Levels | Less than 1 EU per μg by the LAL method. |
| Expression System | HEK293 |
| Gene Id | Q01102 |
| Amino Acid Sequence | Recombinant Mouse P-Selectin/CD62P Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Trp42-Ala709. |
| Storage | -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| View Document | |
| Note | The product is for research use only |
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